FLORIDA SOLID AND HAZARDOUS WASTE REGULATION HANDBOOK: PRIVATE REGULATION


Pleiotrophin Interaction with Synthetic Glycosaminoglycan Mimetics

Chondroitin sulfate (CS) E is the natural ligand for pleiotrophin (PTN) in the central nervous system (CNS) of the embryo.Some structures of PTN in solution have been Gear Shift Extensions solved, but no precise location of the binding site has been reported yet.Using 15N-labelled PTN and HSQC NMR experiments, we studied the interactions with a syn

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ERAP1 Controls the Interaction of the Inhibitory Receptor KIR3DL1 With HLA-B51:01 by Affecting Natural Killer Cell Function

The endoplasmic reticulum aminopeptidase ERAP1 regulates innate and adaptive immune responses by trimming peptides for presentation by major histocompatibility complex (MHC) class I molecules.Previously, we have shown that genetic or pharmacological inhibition of ERAP1 on murine and Champagne Flutes human tumor cell lines perturbs the engagement of

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